If natural remedies are not enough, chemical solutions may be necessary:

Spider:

Insecticides: Use an insecticide specifically designed for insects. Follow label instructions carefully.
Mouse:

Rodenticides: Traps and rodenticides can be effective, but should be used with caution, especially in homes with pets or children.
Traps: Both traps and live traps can be used. Place traps along walls and in areas where you see mouse activity.
Insects:

Insecticides: Use insecticides designed for specific insects (such as cockroach spray and ant killer). Provide proper ventilation and follow safety instructions.
Professional Pest Control: Consider hiring professional pest control services in the event of a severe infestation. They can provide targeted treatments and long-term solutions.

5. Home Guide

To avoid repeating mistakes, consider these long-term strategies:

Regular inspections: Check your home regularly for signs of pests and take immediate action if problems arise.
Landscaping: Take care of your yard and garden. Trim plants and don’t let litter accumulate around your home.
Professional maintenance: Schedule regular visits with a pest specialist to identify and address potential problems before they become worse.